Mechanical model of tissues: Vertex model

To understand mechanical influences in developing and regenerating tissues we are formulating a Vertex model. To investigate how cell-cell contact forces might contribute to the tissue dynamics, we will also consider the influence of extracellular morphogens instructing particular cellular behaviours. Hence, we will develop a multi-scale model combining both, cellular and molecular levels. This model is currently being implemented in a software package. In the near future our package will have an interface with image analysis softwares to incorporate microscopy measurements.

SysBio members involved:
Osvaldo Chara
H. Ariel Alvarez
Emanuel Cura Costa
Alberto Ceccarelli
Augusto Borges
Vanessa Vidal